The mechanisms of action of aminophylline are not completely understood. Objective To compare the efficacy and safety of theophylline or aminophylline for prevention of acute kidney injury (AKI) in neonates and children. Intravenous Aminophylline usually continues for 24+ hours If oral Theophylline commenced: See table below to calculate suggested dose dependent upon Infusion Rate. Even with aminophylline injection still commonly used, the ethylenediamine only serves to increase pH sufficiently to dissolve theophylline at the packaged concentration. (3) Therefore, 250mg aminophylline hydrate = theophylline 200mg. Data sources PubMed/MEDLINE, Embase, Google Scholar and Cochrane renal group were searched from 1970 to … The serum concentration of theophylline was measured by high pressure liquid chromatography. Several sustained-release preparations of theophylline and aminophylline that are absorbed at a constant rate provide steady plasma concentrations over a 12- to 24-hour period . Theophylline is a dimethylxanthine having the two methyl groups located at positions 1 and 3. Aminophylline is a methylated xanthine derivative. Theophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. Product Choice. It is a combination of theophylline (the active component) and ethylenediamine, which is a compound that increases the solubility of theophylline but has no known intrinsic pharmacological effects. As nouns the difference between theophylline and aminophylline is that theophylline is theophylline while aminophylline is a bronchodilator comprising theophylline and ethylenediamine in a 2:1 ratio. Theophylline products are Elixophyllin®, Theobid®, Theo-24®, T … Re-check plasma Theophylline level 3 days after dose adjustment (4-6 hours after morning dose). Theophylline agents include theophylline products and aminophylline products. It has a role as a vasodilator agent, a bronchodilator agent, a muscle relaxant, an EC 3.1.4. Theophylline occurs as bitter-tasting, odorless, white, crystalline powder with a … Theophylline is available in several brands with different dosage schedules. It is structurally similar to caffeine and is found in green and black tea. (2) In practice, a conversion of aminophylline hydrate 1mg = theophylline 0.8mg is used. Design Systematic review and meta-analysis with application of Grading of Recommendations, Assessment, Development and Evaluation system. When given to dogs, it is often dosed at around 4.5 – 5 mg/lb three times daily for symptoms resulting from a mildly collapsed trachea (less than 50% collapsed). 5 Almost identical concentration-time curves were found for theophylline and aminophylline in Aminophylline occurs as bitter-tasting, white or slightly yellow granules or powder with a slight ammoniacal odor and a pK a of 5. Aminophylline is soluble in water and insoluble in alcohol. The recommended doses for bronchodilatation are 200 to 400 mg twice daily, but one-half of these doses may be effective as an antiinflammatory treatment. All dosage and labeling of theophylline formulations should therefore be in terms of the anhydrous theophylline content. Aminophylline hydrate 1.09mg = theophylline 0.86mg. What are theophylline agents ("maintenance" or "long-term control") bronchodilators for chronic obstructive pulmonary disease (COPD)? 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